Mathematical and biological models of blood coagulation

Mathematical and biological models of blood coagulation.

Mathematical and biological models of blood coagulation. A rebuttal.

Overview of Mathematical Models for Blood Flow and Coagulation Process

In this paper we introduce the key properties of blood flow and the blood coagulation process which are essential for their mathematical modelling. After this introduction we review possible approaches to the modelling of blood flow. The conditions of blood flow determine the blood coagulation process because blood flow carries chemical reactants to the area of coagulation. We will introduce th...

Mathematical models of blood coagulation and platelet adhesion: clinical applications.

At present, computer-assisted molecular modeling and virtual screening have become effective and widely-used tools for drug design. However, a prerequisite for design and synthesis of a therapeutic agent is determination of a correct target in the metabolic system, which should be either inhibited or stimulated. Solution of this extremely complicated problem can also be assisted by computationa...

Mathematical modeling and computer simulation in blood coagulation.

Over the last two decades, mathematical modeling has become a popular tool in study of blood coagulation. The in silico methods were able to yield interesting and significant results in the understanding of both individual reaction mechanisms and regulation of large sections of the coagulation cascade. The objective of this paper is to review the development of theoretical research in hemostasi...